Happy & Healthy with Amy

Early Is Everything: Understanding Alzheimer's Prevention Through Prediction

Amy Lang Season 1 Episode 277

Alzheimer's disease begins 10 to 30 years before symptoms appear—which means there's a massive window for prevention if you know your risk factors.

In this first episode of our four-part series on Alzheimer's prevention, Amy shares why "early is everything" when it comes to protecting your brain health, especially for women navigating midlife. Discover how genetic testing can help predict your risk and why our current healthcare system's approach to Alzheimer's is fundamentally backward.

What to Listen For: (10 different points)

  1. [00:00:00] Why Amy's personal experience with her mother's Alzheimer's diagnosis in 2016 drove her to research prevention.
  2. [00:03:00] The three tiers of prevention in healthcare: primary, secondary, and tertiary—and why Alzheimer’s care is fundamentally backwards.
  3. [00:07:00] The shocking reality: by the time Alzheimer’s symptoms appear, 20% of the hippocampus is already damaged.
  4. [00:10:00] How insurance companies limit early testing and what you can do about it.
  5. [00:13:00] Understanding preclinical vs. clinical Alzheimer's and why the preclinical phase offers a huge window for intervention.
  6. [00:15:00] The three-phase model of Alzheimer’s: amyloid plaques, tau tangles, and neuroinflammation—explained.
  7. [00:19:00] Why 50 million Americans could already have preclinical Alzheimer's without knowing it.
  8. [00:21:00] Genetic factors like APOE4 and their impact on your risk of developing Alzheimer's.
  9. [00:24:00] Blood biomarkers for detection: what they reveal and why they’re underused.
  10. [00:25:00] Why lifestyle changes are just as actionable as new drugs for Alzheimer's prevention.

By understanding your genetic risks, you can take meaningful action long before symptoms appear. Tune in to learn more about how to protect your brain health.

Don't forget to subscribe for the rest of this series!

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