Happy & Healthy with Amy

Leqembi or Kisunla: How Early Can You Get Treatment?

• Amy Lang • Season 2 • Episode 61

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If Alzheimer’s starts in the brain years—sometimes decades—before symptoms appear, why wait until memory problems begin to treat it?

That’s the question behind today’s episode.

The newer Alzheimer’s drugs Leqembi and Kisunla appear to offer the most promising results when treatment starts early. But “early” doesn’t currently mean before symptoms.

So how early can you take them?

In this episode, Amy explains where the treatment window begins today, why these anti-amyloid drugs aren’t currently approved for people with preclinical Alzheimer’s disease, and what researchers are studying to determine whether that could change.

You’ll also learn why having amyloid in your brain does not guarantee that you’ll develop dementia—and why being too early for medication doesn’t mean you’re too early to take meaningful action to protect your brain.

In this episode, you’ll learn:

  • How early you can currently start Leqembi or Kisunla
  • The difference between MCI, mild dementia, and preclinical Alzheimer’s disease
  • Why doctors need to confirm that amyloid is present before prescribing an anti-amyloid treatment
  • Why earlier treatment within the current treatment window may produce more promising results
  • How amyloid, tau, inflammation, and neurodegeneration fit into Alzheimer’s progression
  • Why removing amyloid later in the disease process may have less impact
  • What the AHEAD 3-45 and TRAILBLAZER-ALZ 3 prevention trials are trying to discover
  • Why amyloid in the brain does not automatically mean dementia is inevitable
  • The risks and treatment burden that must be weighed against the potential benefits of earlier treatment
  • What you can start doing today if your goal is to prevent or delay cognitive decline

Download Amy’s free RESTORED Protocol:
amylangcoaching.com

Use it to assess the major lifestyle areas that support brain health and identify the next step you can take toward building an Alzheimer’s-resistant brain.

Related episodes:
Listen to Amy’s Leqembi and Kisunla series, including:

Memory and thinking problems do not automatically mean Alzheimer’s disease. There are multiple possible causes of cognitive impairment, including conditions that may be treatable or potentially reversible.

And if Alzheimer’s is the cause, the disease-modifying treatments available today are designed specifically for the early symptomatic stages.

Talk with a qualified healthcare professional or ask for a referral to a neurologist.

This podcast is for educational purposes only and is not medical advice.

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